Why Delta Air Lines Workers Are Fighting for a Union — Although Delta offered boarding pay, flight attendants say they don’t get paid during delays or for “sits” between flights. “Our boarding pay is so sad, it’s like half of our regular pay for half of the time that we’re boarding,”
After more than three decades of planning and a $250 million investment, Lykos Therapeutics’ application for the first psychedelic drug to reach federal regulators was expected to be a shoo-in. Lykos, the corporate arm of a nonprofit dedicated to winning mainstream acceptance of psychedelics, had submitted data to the Food and Drug Administration showing that its groundbreaking treatment for post-traumatic stress disorder — MDMA plus talk therapy — was significantly more effective than existing treatments. […] two dozen scientists, doctors and trauma survivors told an F.D.A. advisory panel how MDMA-assisted therapy had brought marked relief from a mental health condition associated with high rates of suicide, especially among veterans. Then came skeptics with disturbing accusations: that Lykos was “a therapy cult,” that practitioners in its clinical trials had engaged in widespread abuse of participants and that the company had concealed a litany of adverse events. […] Dr. Devenot and six others presented themselves as experts in the field of psychedelics, but none had expertise in medicine or therapy. Nor had the speakers disclosed their connection to Psymposia, a leftist advocacy group whose members oppose the commercialization of psychedelics and had been campaigning against Lykos and its nonprofit parent […] The critics did not provide evidence to back their claims of systematic wrongdoing, but when the votes were counted that day, the panel overwhelmingly rejected Lykos’s application. [NY Times]
In 1984, Dr. Daniel Drucker, an endocrinologist from the University of Toronto, discovered a hormone in the human gut that helped pave the way for popular diabetes drugs such as Novo Nordisk’s Ozempic and Wegovy. […] GLP-1 quickly disappears from the human body, positing difficulties in drug development […] Here enters the Gila monster, the largest lizard in North America […] Hormones in this reptile’s venom had also previously been shown to regulate blood sugar. Drucker wanted to know why and honed his research using venom from the Gila Monster. […] “We tried using lizard DNA that was in the freezer in Toronto at the Royal Ontario Museum and the cloning didn’t work. And so our next step was to try and get a live lizard and obviously these are difficult to obtain, you can’t walk into a pet store in Toronto and order these things.” […] After experimenting on the lizard, Drucker and his team found that these reptiles are “very unique in that it has genes for Exendin-4, the protein that became the first diabetes GLP-1 treatment”
Gesture-based age estimation tool BorderAge joins Australia age assurance trial — Originally born out of research on a tool to test for doping in sports, BorderAge works on the principle that as we age, our body changes – and so do the ways that we move. Technically, it measures variations among people of different ages in the duration and distance of “rapid aimed limb movements toward a visible target region.” The process can be completed with less than 30 seconds of footage from a smartphone camera.
this paper proposes a comprehensive concept of secondary psychosis spectrum disorder, demonstrating that stress reactions and depression serve as a common foundation for these disorders
Thomas Aquinas’ Appearance Revealed After 750 Years The lead author of the study, Brazilian 3D designer Cicero Moraes, has reconstructed the faces of other saints […] “The most challenging part was projecting the missing regions of the skull. Fortunately, we have tools for this, based on measurements taken from CT scans of living people.”
Tom Robbins dies at 92. He blended pop philosophy and absurdist comedy in best-selling books like “Even Cowgirls Get the Blues” and “Skinny Legs and All.” […] His story lines were secondary and hard to explain; one reads a Tom Robbins novel for the verve of a well-wrought sentence, not a taut narrative. His literary currency was exaggeration, irony, bathos and the comic mythopoetic, combined for an effect that was truly his own. Take a representative line like this, from “Even Cowgirls Get the Blues,” his second novel: “An afternoon squeezed out of Mickey’s mousy snout, an afternoon carved from mashed potatoes and lye, an afternoon scraped out of the dog’s dish of meteorology.”
there’s a very good chance that a dying person will be delirious at the end of life. In fact, in palliative care and hospice spaces, 58 to 88 percent of cancer patients are delirious in the last week to hours before death. […] as you die, unless you die very suddenly in an instant, your various bodily systems start to work differently until they stop working at all. And that includes the way that you think, and that includes the way that you communicate.” […] the exact biological mechanisms behind delirium aren’t well understood, but it appears to stem from neuronal dysfunction, probably due to neurotransmitter fluctuations. Neurons in the brain aren’t dying (which is why sometimes people can recover from delirium) but disconnecting from each other.
[2022] a 70-year-old woman in the central east Indian state of Odisha was killed by an elephant, only to have the same elephant reportedly return to her funeral to pull her body from a pyre and trample her again before fleeing