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science

The Kreutzer Sonata

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“Withdrawal is the most problematic for relationships,” Sanford said. “It’s a defensive tactic that people use when they feel they are being attacked, and there’s a direct association between withdrawal and lower satisfaction overall with the relationship.”

Meanwhile, “passive immobility” — expecting your partner to be a mind-reader — is a tactic people use when they feel anxious in a relationship, and it makes it especially difficult for couples to make progress toward resolving conflicts. But it may not be as harmful down the line as withdrawal, he said.

{ EurekAlert | Continue reading }

art { Mel Ramos, Elephant Seal, 1970 }

‘Everyone is the other, and no one is himself.’ –Heidegger

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Some people will tell you that they have a clear sense of who they are, and that their sense of self is stable over time. Psychologists refer to this as having high “self-concept clarity.” In a new study, Jean Guerrettaz and Robert Arkin shine a spotlight on these self-proclaimed self-knowers. The researchers find that their confidence is often fragile, and that somewhat paradoxically, it is people confident in their sense of self whose self-esteem is most undermined by challenging questions about who they are.

{ BPS | Continue reading }

Only the whole is true

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Monozygotic twins are considered being genetically identical, therefore they cannot be differentiated using standard forensic DNA testing. Here we describe how identification of extremely rare mutations by ultra-deep next generation sequencing can solve such cases. We sequenced DNA from sperm samples of two twins and from a blood sample of the child of one twin. Bioinformatics analysis revealed five single nucleotide polymorphisms (SNPs) present in the twin father and the child, but not in the twin uncle.

Our results give experimental evidence for the hypothesis that rare mutations will occur early after the human blastocyst has split into two, the origin of twins, and that such mutations will be carried on into somatic tissue and the germline. The method provides a solution to solve paternity and forensic cases involving monozygotic twins as alleged fathers or originators of DNA traces.

{ FSI Genetics }

‘We live among ideas much more than we live in nature.’ —Saul Bellow

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DNA is generally regarded as the basic building block of life itself. In the most fundamental sense, DNA is nothing more than a chemical compound, albeit a very complex and peculiar one. DNA is an information-carrying molecule. The specific sequence of base pairs contained in a DNA molecule carries with it genetic information, and encodes for the creation of particular proteins. When taken as a whole, the DNA contained in a single human cell is a complete blueprint and instruction manual for the creation of that human being.

In this article we discuss myriad current and developing ways in which people are utilizing DNA to store or convey information of all kinds. For example, researchers have encoded the contents of a whole book in DNA, demonstrating the potential of DNA as a way of storing and transmitting information. In a different vein, some artists have begun to create living organisms with altered DNA as works of art. Hence, DNA is a medium for the communication of ideas. Because of the ability of DNA to store and convey information, its regulation must necessarily raise concerns associated with the First Amendment’s prohibition against the abridgment of freedom of speech.

New and developing technologies, and the contemporary and future social practices they will engender, necessitate the renewal of an approach towards First Amendment coverage that takes into account the purposes and values incarnated in the Free Speech Clause of the Constitution.

{ Charleston School of Law | Continue reading }

photo { Bruce Davidson }

The Ravens. The Five Satins. The Delphonics. The Cadillacs. The Crests. The Del Rays.

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Machiavellianism is a personality trait characterized by a manipulative interpersonal style, emotional detachment and suspicion of others. Individuals with high levels of Machiavellianism navigate through their social relationships with  protective self-monitoring, external orientated thinking and confidence in their ability to deceive which facilitates their willingness to exploit others for their own self-serving goal. Not surprisingly, research has found that Machiavellianism relates to lower quality friendships in adulthood, including relational aggression in online relationships. […]

Previous research has established the importance of parental bonding (i.e.,  parental care and overprotection) for the development of personality traits and adult relationships. The current study investigated the influence of recalled parenting on the development of Machiavellianism and adult friendship quality. […] Path modeling suggests that decreased maternal care and increased paternal overprotection relate to Machiavellianism which is associated with lower adult friendship quality.

{ Individual Differences Research | Continue reading }

The sound of a billion jaws collectively hitting the floor

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[T]he Inuit, the Masai, and the Samburu people of Uganda all originally ate diets that were 60-80% fat and yet were not obese and did not have hypertension or heart disease.

The hypothesis that saturated fat is the main dietary cause of cardiovascular disease is strongly associated with one man, Ancel Benjamin Keys, a biologist at the University of Minnesota. […] Keys launched his “diet-heart hypothesis” at a meeting in New York in 1952, when the United States was at the peak of its epidemic of heart disease, with his study showing a close correlation between deaths from heart disease and proportion of fat in the diet in men in six countries (Japan, Italy, England and Wales, Australia, Canada, and the United States). Keys studied few men and did not have a reliable way of measuring diets, and in the case of the Japanese and Italians he studied them soon after the second world war, when there were food shortages. Keys could have gathered data from many more countries and people (women as well as men) and used more careful methods, but, suggests Teicholz, he found what he wanted to find. […]

At a World Health Organization meeting in 1955 Keys’s hypothesis was met with great criticism, but in response he designed the highly influential Seven Countries Study, which was published in 1970 and showed a strong correlation between saturated fat (Keys had moved on from fat to saturated fat) and deaths from heart disease. Keys did not select countries (such as France, Germany, or Switzerland) where the correlation did not seem so neat, and in Crete and Corfu he studied only nine men. […]

[T]he fat hypothesis led to a massive change in the US and subsequently international diet. One congressional staffer, Nick Mottern, wrote a report recommending that fat be reduced from 40% to 30% of energy intake, saturated fat capped at 10%, and carbohydrate increased to 55-60%. These recommendations went through to Dietary Guidelines for Americans, which were published for the first time in 1980. (Interestingly, a recommendation from Mottern that sugar be reduced disappeared along the way.)

It might be expected that the powerful US meat and dairy lobbies would oppose these guidelines, and they did, but they couldn’t counter the big food manufacturers such as General Foods, Quaker Oats, Heinz, the National Biscuit Company, and the Corn Products Refining Corporation, which were both more powerful and more subtle. In 1941 they set up the Nutrition Foundation, which formed links with scientists and funded conferences and research before there was public funding for nutrition research. […]

Saturated fats such as lard, butter, and suet, which are solid at room temperature, had for centuries been used for making biscuits, pastries, and much else, but when saturated fat became unacceptable a substitute had to be found. The substitute was trans fats, and since the 1980s these fats, which are not found naturally except in some ruminants, have been widely used and are now found throughout our bodies. There were doubts about trans fats from the very beginning, but Teicholz shows how the food companies were highly effective in countering any research that raised the risks of trans fats. […]

Another consequence of the fat hypothesis is that around the world diets have come to include much more carbohydrate, including sugar and high fructose corn syrup, which is cheap, extremely sweet, and “a calorie source but not a nutrient.”2 5 25 More and more scientists believe that it is the surfeit of refined carbohydrates that is driving the global pandemic of obesity, diabetes, and non-communicable diseases.

{ The BMJ | Continue reading }

related { Beware the Man of One Study }

image { Isa Genzken, X-ray, 1991 }

‘To do nothing is sometimes a good remedy.’ –Hippocrates

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We all know that exercise can make us fitter and reduce our risk for illnesses such as diabetes and heart disease. But just how, from start to finish, a run or a bike ride might translate into a healthier life has remained baffling.

Now new research reports that the answer may lie, in part, in our DNA. Exercise, a new study finds, changes the shape and functioning of our genes, an important stop on the way to improved health and fitness. […]

Epigenetics [is] a process by which the operation of genes is changed, but not the DNA itself. Epigenetic changes occur on the outside of the gene, mainly through a process called methylation. In methylation, clusters of atoms, called methyl groups, attach to the outside of a gene like microscopic mollusks and make the gene more or less able to receive and respond to biochemical signals from the body.

Scientists know that methylation patterns change in response to lifestyle. Eating certain diets or being exposed to pollutants, for instance, can change methylation patterns on some of the genes in our DNA and affect what proteins those genes express. Depending on which genes are involved, it may also affect our health and risk for disease. […]

The volunteers pedaled one-legged at a moderate pace for 45 minutes, four times per week for three months. […] More than 5,000 sites on the genome of muscle cells from the exercised leg now featured new methylation patterns. Some showed more methyl groups; some fewer. […]

Most of the genes in question are known to play a role in energy metabolism, insulin response and inflammation within muscles. In other words, they affect how healthy and fit our muscles — and bodies — become.

They were not changed in the unexercised leg.

{ NY Times | Continue reading }

photo { David Hasselhoff, The SpongeBob Squarepants Movie, 2004 }

related { Phobias may be memories passed down in genes from ancestors }

Baby baby baby, look to the sky, seeking to find, the third eye

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Impending fatherhood can lower two hormones–testosterone and estradiol–for men, even before their babies are born, a new University of Michigan study found.

Other studies indicate that men’s hormones change once they become fathers, and there is some evidence that this is a function of a decline after the child’s birth. […]

Expectant mothers experience significant hormone changes throughout the transition to parenthood, but less has been known about the prenatal hormone changes among soon-to-be fathers.

Women showed large prenatal increases in all four hormones, while men saw declines in testosterone (which is associated with aggression and parental care) and estradiol (which is associated with caregiving and bonding). No changes were found in men’s cortisol (a stress hormone) or progesterone (which is associated with social closeness and maternal behavior).

{ EurekAlert | Continue reading }

sculpture { Duane Hanson, Old Man Playing Solitaire, 1973 }

Thus I enforce thy rotten jaws to open, and in despite I’ll cram thee with more food!

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In a recent study, Mann and some colleagues induced a bad mood in 100 college students by making them watch clips from sad movies. They then fed half the students their favorite comfort food, while the other students ate food they enjoyed, but wouldn’t consider comfort food.

Once the students had finished eating, the researchers asked the students how they felt. It turns out all the students felt better, regardless of what they had eaten.

In another experiment, Mann had half the kids eat comfort food, and the other half eat nothing. After a few minutes, both groups felt equally better. The comfort food had no effect on mood.

{ NPR | Continue reading }

photo { Tania Oldyork }

‘Let’s break shit.’ –Guy Vidra

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The Male Idiotic Theory (MIT) stipulates that the reason men are more prone to injury and death is simply because they “are idiots and idiots do stupid things“. Despite tons of anecdotal evidence confirming MIT, there’s never been a systematic analysis on sex differences in idiotic risk taking behaviour. Until now.

In a new study published in BMJ, researchers obtained 20 years worth of data from the Darwin Awards to tally up the sex of each year’s winner. For those not in the know, the Darwin Awards are given to people who die in such astonishingly stupid ways that “their action ensures the long-term survival of the species, by selectively allowing one less idiot to survive”. […]

Men made up a staggering 88.7 % of Darwin Award winners in 318 examined cases.

{ Neurorexia | Continue reading }

related { Males are more likely to die than females while in the womb }

They charged me 15 dollars. That’s how much it costs to only have 20 dollars.

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This research proposes that because rounded numbers are more fluently processed, rounded prices (e.g., $200.00) encourage reliance on feelings.

In contrast, because nonrounded numbers are disfluently processed, nonrounded prices (e.g., $198.76) encourage reliance on cognition.

Thus, rounded (nonrounded) prices lead to a subjective experience of “feeling right” when the purchase decision is driven by feelings (cognition).

Further, this sense of feeling right resulting from the fit between the roundedness of the price number and the nature of decision context can make positive reactions toward the target product more positive and negative reactions more negative, a phenomenon referred to as the rounded price effect in the current research.

Results from five studies provide converging evidence for the rounded price effect. Findings from the current research further show that merely priming participants with rounded (nonrounded) numbers in an unrelated context could also lead to the rounded price effect.

Finally, this research provides process support by showing that the rounded price effect is mediated by a sense of feeling right.

{ Journal of Consumer Research }

photo { Photo Frances McLaughlin-Gill, Woman wearing yellow coat, scarf, hat, gloves and skirt, 1947 }

‘Anaxagoras agrees with Leucippus and Democritus that the elements are infinite.’ –Aristotle

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New theories suggest the big bang was not the beginning, and that we may live in the past of a parallel universe.

[…]

Time’s arrow may in a sense move in two directions, although any observer can only see and experience one.

{ Scientific American | Continue reading }

photo { Tania Shcheglova and Roman Noven }

Is a dream autobiography or fiction?

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10 of The Most Counter-intuitive Psychology Findings Ever Published

1. Self-help Mantras Can Do More Harm Than Good

[…]

3. Criminals Show Cooperation and Prosocial Behaviour in Economic Games

[…]

5. We Make Many Decisions Mindlessly

[…]

6. Opposites Don’t Attract

[…]

10. Sometimes a Pregnant Woman’s Depression is Advantageous For Her Baby

{ BPS | full story }

‘In yer face turbo rave.’ –808 State

{ Guilt and expected guilt in the door-in-the-face technique | PDF | via Improbable }

‘When I don’t have red, I use blue.’ –Picasso

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Ivan Pavlov is best known as a founding figure of behaviorism who trained dogs to salivate at the sound of a bell. […] Pavlov didn’t use a bell, and for his real scientific purposes, couldn’t. English-speakers think he did because of a mistranslation of the Russian word for zvonok (buzzer). […]

Although one would expect that this investigator of reflexive reactions would think otherwise, he believed in free will. […]

He didn’t win his Nobel Prize (1904) for research on conditional reflexes, but rather for his studies of digestive physiology.

{ Oxford University Press | Continue reading | More: New Yorker }

‘I have no knowledge of myself as I am, but merely as I appear to myself.’ –Kant

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[P]eople who are depressed display some surprising advantages in their thinking skills. Depressed people:

1. process information more deeply.
2. are more accurate at complex tasks.
3. make better judgements on detail-oriented information.
4. make more accurate cost-benefit analyses.

The researchers developed a new questionnaire which measures ‘analytical rumination’, a mental process which is thought to be an ancient defence mechanism and the root of depression.

Analytical rumination is where people turn problems over in their heads to the exclusion of all else, trying to look for a solution.

They first examine the problem’s cause, then the things that need solving, any possible solutions plus the costs and benefits of each solution.

The symptoms of depression, which often include lethargy, difficulty sleeping, poor concentration and disinterest in other people or the external world, may actually be ways of saving energy while a person is focusing on the problem.

{ PsyBlog | Continue reading }

What are your unbreakable rules for yourself?

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Researchers in the US have used electrical brain stimulation to boost the vigilance of sleep-deprived military personnel working on an airforce base.

Experiments on 18- to 42-year old men and women on active duty found that half an hour of electrical brain stimulation improved their performance twice as much as caffeine, and the effect lasted three times as long.

{ The Guardian | Continue reading | via gettingsome }

‘What does a woman want?’ –Freud

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[T]he patient was a woman who, although she was being examined in my office at New York Hospital, claimed we were in her home in Freeport, Maine. The standard interpretation of this syndrome is that she made a duplicate copy of a place (or person) and insisted that there are two. […]

This woman was intelligent; before the interview she was biding her time reading the New York Times. I started with the ‘So, where are you?’ question. ‘I am in Freeport, Maine. I know you don’t believe it. Dr Posner told me this morning when he came to see me that I was in Memorial Sloan-Kettering Hospital. […] Well, that is fine, but I know I am in my house on Main Street in Freeport, Maine!’ I asked, ‘Well, if you are in Freeport and in your house, how come there are elevators outside the door here?’

The grand lady peered at me and calmly responded, ‘Doctor, do you know how much it cost me to have those put in?’ […]

Because of her lesion the part of the brain that represents locality is overactive and sending out an erroneous message about her location. The interpreter is only as good as the information it receives, and in this instance it is getting a wacky piece of information.

{ NeuroDojo | Continue reading }

‘Truth is always strange—stranger than fiction.’ –Lord Byron

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We all resist changing our beliefs about the world, but what happens when some of those beliefs are based on misinformation? Is there a right way to correct someone when they believe something that’s wrong? […]

The first thing their review turned up is the importance of “backfire effects” — when telling people that they are wrong only strengthens their belief. […]

If you try and debunk a myth, you may end up reinforcing that belief, strengthening the misinformation in people’s mind without making the correct information take hold.

What you must do, they argue, is to start with the plausible alternative (that obviously you believe is correct). If you must mention a myth, you should mention this second, and only after clearly warning people that you’re about to discuss something that isn’t true.

{ Tom Stafford/BBC | Continue reading }

The time is out of joint

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O’Brian oversees America’s master clock. It’s one of the most accurate clocks on the planet: an atomic clock that uses oscillations in the element cesium to count out 0.0000000000000001 second at a time. If the clock had been started 300 million years ago, before the age of dinosaurs began, it would still be keeping time — down to the second. […]

At the nearby University of Colorado Boulder is a clock even more precise than the one O’Brian watches over. […] This new clock can keep perfect time for 5 billion years.”It’s about the whole, entire age of the earth,” says Jun Ye, the scientist here at JILA who built this clock. […]

But this new clock has run into a big problem: This thing we call time doesn’t tick at the same rate everywhere in the universe. Or even on our planet.

Right now, on the top of Mount Everest, time is passing just a little bit faster than it is in Death Valley. That’s because speed at which time passes depends on the strength of gravity. Einstein himself discovered this dependence as part of his theory of relativity, and it is a very real effect.

The relative nature of time isn’t just something seen in the extreme. If you take a clock off the floor, and hang it on the wall, Ye says, “the time will speed up by about one part in 1016.” […] Time itself is flowing more quickly on the wall than on the floor. These differences didn’t really matter until now. But this new clock is so sensitive, little changes in height throw it way off. Lift it just a couple of centimeters, Ye says, “and you will start to see that difference.” […]

The world’s current time is coordinated between atomic clocks all over the planet. But that can’t happen with the new one.

{ NPR | Continue reading }

photo { Petra Collins }



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