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XYY syndrome is an aneuploidy (abnormal number) of the sex chromosomes in which a human male receives an extra Y-chromosome.
Some medical geneticists question whether the term “syndrome” is appropriate for this condition because its clinical phenotype is normal and the vast majority (an estimated 97% in Britain) of 47,XYY males do not know their karyotype.
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Triple X syndrome is a form of chromosomal variation characterized by the presence of an extra X chromosome in each cell of a human female. The condition occurs only in females. […]
Because of the lyonization, inactivation, and formation of a Barr body in all female cells, only one X chromosome is active at any time. Thus, Triple X syndrome most often has only mild effects, or has no unusual effects at all.
Symptoms may include tall stature; small head (microcephaly); vertical skinfolds that may cover the inner corners of the eyes (epicanthal folds); delayed development of certain motor skills, speech and language; learning disabilities, such as dyslexia; or weak muscle tone.
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Klinefelter syndrome, or XXY syndrome, is a genetic disorder in which there is at least one extra X chromosome to a standard human male karyotype, for a total of 47 chromosomes rather than the 46 found in genetically normal humans. […]
This chromosome constitution exists in roughly between 1:500 to 1:1000 live male births but many of these people may not show symptoms. […]
Affected males are often infertile, or may have reduced fertility. […] XXY males are also more likely than other men to have certain health problems, which typically affect females, such as breast cancer and osteoporosis.
photos { Frieke Janssens }
