PKMzeta
Although the murder rate is insulated from reporting and definition shifts, it is very strongly affected by medical care – both improved techniques and better access. A fatal injury in 1960 might be easily treatable today. To put it in concrete numbers: if aggravated assaults in the United States had been as lethal in 1999 as they were in 1960, the murder rate would have been 3.4 times higher
Brain Scientists Finally Discover the Glue that Makes Memories Stick for a Lifetime — The persistence of memory is crucial to our sense of identity, and without it, there would be no learning, for us or any other animal. […] PKMzeta (protein kinase Mzeta) is short-lived. “Those proteins only last in synapses for a couple of hours, and in neurons, probably a couple of days […] Yet our memories can last 90 years, so how do you explain this difference?” […] Each neuron has around 10,000 synapses, only a few percent of which are strengthened. The strengthening of some synapses and not others is how this mechanism stores information. “It’s not PKMzeta that’s required for maintaining a memory, it’s the continual interaction between PKMzeta and this targeting molecule, called KIBRA. If you block KIBRA from PKMzeta, you’ll erase a memory that’s a month old.”