nswd



Poison gas? That’s the weapon of a coward, and you know it.

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On January 14th, a 39-year-old computer engineer was admitted to Princeton University Hospital in New Jersey with nagging, flu-like symptoms. The man was nauseated, suffering from severe joint pains, wracked by a strange, convulsive trembling in his legs. Doctors at the hospital tried one treatment after another but Xiaoye Wang only became weaker.

Finally, a nurse at the hospital stepped hesitantly forward. She remembered a 1995 case in China in which a student at Beijing University became mysteriously ill. The cause was eventually found to be poisoning by the  toxic element thallium. The young woman received a life-saving antidote although she suffered lingering disabilities from the attack.

And – as the nurse recalled from the highly publicized case – the student’s symptoms were eerily similar to Wang’s. (…) The Princeton doctors were dubious about a fairly exotic poison use, but they were running out of ideas. So they agreed to send Wang’s blood and urine samples out of state. And to their shock, the tests proved the nurse right. The lab had discovered a shockingly high level of thallium in Wang’s body. (…)

Thallium is a dangerous and carefully regulated poison, once widely available but mostly found in laboratories these days. “It’s either attempted suicide or homicide,” said Steven Marcus, head of the poison control center. He added that he knew of only one good antidote for thallium poisoning, a medication called Prussian Blue.

Rather ironically, the antidote’s name derives from another famously lethal substance. Prussian Blue refers to cyanide (a component of the medication) which can be used to produce a royal blue pigment. Some cyanide formulas are very deadly, notably hydrogen cyanide or potassium cyanide. But mixed into the tidy antidote formula (brand name Radiogardase) cyanide merely becomes part of a chemical chain that wraps itself around thallium, binding it up, and allowing the body to remove the poison.

By the time, the New Jersey doctors were able to secure the antidote though, it was too late. Wang was deep into a coma; he died on January 26 leaving doctors – and now criminal investigators – to answer the question raised by Steven Marcus. Was it suicide or was it murder?

{ PLoS | Continue reading }





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